Efek Pemberian Gentamisin Secara Oral Terhadap Kadar Asam Urat, Ureum, dan Kreatinin Tikus Wistar

Ardiansyah, Syahrul and Hanum, Galuh Ratmana (2018) Efek Pemberian Gentamisin Secara Oral Terhadap Kadar Asam Urat, Ureum, dan Kreatinin Tikus Wistar. Universitas Muhammadiyah Surabaya, Surabaya.

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Abstract

Gentamicin is an aminoglycoside class of antibiotics which at high doses can cause damage to the kidneys. This research was to determine the levels of BUN, creatinine and amino acids after gentamicin induction. This research is experimental with gentamicin test material given to male rats as much as 0.3 ml/day for 7 and 10 days. Blood serum levels were then measured for BUN, creatinine and amino acids using a photometer microlab 300. The results showed that after doing treatment for 7 days the average value of BUN levels increase from 21.7 to 36.3 mg/dl, creatinine increase from 0, 88 to 1.9 mg/dl, uric acid increase from 1.54 to 4.29 mg/dl. It was concluded that giving of gentamicin as much as 0.3 ml/day for 7 and 10 days increased BUN levels, creatinine and uric acid exceeded the normal limit.

Item Type:	Other
Subjects:	Q Science > QP Physiology
Divisions:	Faculty of Health Science > School of Health Analyst
Depositing User:	Syahrul FIkes
Date Deposited:	13 Mar 2019 08:12
Last Modified:	13 Mar 2019 08:12
URI:	http://eprints.umsida.ac.id/id/eprint/5956

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