THE INFLUENCE OF THE METHOD OF MATERIAL COLLECTION ON THE RESULTS OF CYTOMORPHOLOGICAL EXAMINATION IN THE DIAGNOSIS OF NEOPLASMS OF THE ORAL MUCOSA

Chirag, Darji and Khujakulov, Sh.Sh. and Dusmurodova, Sh.Sh. (2025) THE INFLUENCE OF THE METHOD OF MATERIAL COLLECTION ON THE RESULTS OF CYTOMORPHOLOGICAL EXAMINATION IN THE DIAGNOSIS OF NEOPLASMS OF THE ORAL MUCOSA. European Journal of Modern Medicine and Practice, 5 (1). pp. 157-164. ISSN 2795-921X

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Abstract

The oral mucosa and underlying tissues have a complex anatomical structure, which determines the specificity of the clinical course and treatment of tumors developing here. Malignant tumors that occur in the oral cavity, in most cases, have a structure of squamous cell keratinizing cancer. In a dental clinic, diagnostics of precancerous and tumor changes presents serious difficulties, the main reason for which is the low oncological alertness of dentists, as well as the lack of the necessary equipment and modern minimally invasive methods for early detection of cancer. Histological examination is rarely used in dentistry, since it involves the intravital collection of pathological tissue (biopsy) and has a number of disadvantages associated with the work with a sharp instrument, the possibility of bleeding, errors in collecting material, and the duration of waiting for the result from the pathologist. Considering the external localization of neoplasms of the ORAL MUCOSA and KCG, the procedure for collecting material for cytological examination is simple and highly sensitive (the sensitivity of the methodis 90-95%).Aim: assessment of the possibility of cytological diagnostics in the practical activities of a dentist and the influence of various methods of collecting material on the results of morphological analysis.Materials and methods of research. A total of 114 samples from 38 patients who sought dental care with complaints of neoplasms in the oral cavity were analyzed. Material from each patient was collected in three ways with subsequent cytological examination.Results. The obtained results indicate that the lowest percentage of detection of malignant changes in the cells of patients was observed with self-washing from the oral mucosaes, and the highest percentage of pathologically altered cells was detected when collecting material using the smear print method. The obtained results of the cytological study were compared with the histological data, where various percentage matches were revealed depending on the method of collecting the material.Conclusion: the use of the cytological method of research in dental practice with adequate material collection allows to identify malignant changes in cells in more than 80% of cases.EUROPEAN JOURNAL OFMODERNMEDICINEAND PRACTICEVol. 5No. 1(Jan-2025) EJMMPISSN: 2795-921X

Item Type:	Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Postgraduate > Master's of Management
Depositing User:	Journal Editor
Date Deposited:	27 Jan 2025 11:02
Last Modified:	27 Jan 2025 11:02
URI:	http://eprints.umsida.ac.id/id/eprint/15317

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