REDUCING GRAM-NEGATIVE RESISTANCE THROUGH BETA-LACTAM DE-ESCALATION IN SEPSIS

Davlatov, Sh.Q (2024) REDUCING GRAM-NEGATIVE RESISTANCE THROUGH BETA-LACTAM DE-ESCALATION IN SEPSIS. Journal of Healthcare and Life-Science Research, 4 (1). pp. 169-172. ISSN 2181-4368

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Abstract

The increasing prevalence of gram-negative resistance poses a significant challenge in the management of sepsis, leading to poor patient outcomes and increased healthcare costs. This study explores the effectiveness of beta-lactam de-escalation as a strategy to reduce gram-negative resistance in patients withsepsis. A cohort of sepsis patients treated with broad-spectrum antibiotics was analyzed, with de-escalation practices implemented based on culture results and clinical stability. The findings suggest that targeted beta-lactam de-escalation not only reduces resistance rates but also improves clinical outcomes and antibiotic stewardship. This approach may serve as a critical tool in combating antimicrobial resistance globally.

Item Type:	Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Postgraduate > Master's of Management
Depositing User:	Journal Editor
Date Deposited:	05 Mar 2025 10:43
Last Modified:	05 Mar 2025 10:43
URI:	http://eprints.umsida.ac.id/id/eprint/15762

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