Preparation and Characterization of Some 1,3-Oxazepane -7,4-Dione Derivatives and Evaluation of their Biological Activity

Hamid Mohammed Saleh, Al-Jubori (2024) Preparation and Characterization of Some 1,3-Oxazepane -7,4-Dione Derivatives and Evaluation of their Biological Activity. European Journal of Modern Medicine and Practice, 4 (4). pp. 333-343. ISSN 2795-921X

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Abstract

This study included the preparation of chaff bases using terephthaldehyde as a nucleus, reacting them with amine substitutes, and then reacting the resulting compounds with succinic anhydride in the presence of dry benzene as a solvent to obtain a heptad ring derived from oxazepane, whose biological effectiveness was tested against two types of gram-positive and gram-negative bacteria. The structures were validated using physical measurements. From the melting point, color change, and product percentage spectroscopic analyses, including proton nuclear magnetic resonance and infrared spectroscopy, were employed.

Item Type: Article
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Postgraduate > Master's of Islamic Education
Depositing User: Journal Editor
Date Deposited: 03 Mar 2025 08:27
Last Modified: 03 Mar 2025 08:27
URI: http://eprints.umsida.ac.id/id/eprint/15677

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