Effectiveness of Anticoagulants in Atrial Fibrillation in Patients with Chronic Heart Failure

Avazbekov, B.A. and Tulaboeva, G. M. and Tursunov, X.X. and Sobirova, Sh.S (2024) Effectiveness of Anticoagulants in Atrial Fibrillation in Patients with Chronic Heart Failure. International Journal of Integrative and Modern Medicine, 2 (12). pp. 288-290. ISSN 2995-5319

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Abstract

Effective treatment of atrial fibrillation (AF) must begin with the initiation of anticoagulant therapy (ACT) [1]. A key component of managing patients with both AF and heart failure (HF)—especially with the growing prevalence of procedures like cardioversion or catheter ablation (CA)—is the accurate prescription of ACT and continuous monitoring throughout the treatment process.The coexistence of AF and HF significantly increases the risk of stroke, irrespective of left ventricular ejection fraction (LVEF), leading to higher mortality rates [30, 31]. An irregular ventricular rhythm during AF can elevate pressure in the pulmonary capillaries, disturb homeostasis, and impair overall hemodynamics. The activation of the renin-angiotensin-aldosterone system and cytokines during HF plays a major role in this process. Together, these hemodynamic, neurohormonal, and electrophysiological factors worsen the pathological conditions in patients with both AF and HF, thereby activating all components of Virchow’s triad and increasing the risk of thrombosis

Item Type:	Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Postgraduate > Master's of Management
Depositing User:	Journal Editor
Date Deposited:	05 Jan 2025 10:19
Last Modified:	05 Jan 2025 10:19
URI:	http://eprints.umsida.ac.id/id/eprint/15115

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